Atomic mutagenesis of the ribosome

 

Further reading (reviews only)

  • Willi J., Küpfer P., Evéquoz D., Fernandez G., Katz A., Leumann Ch. and Polacek N. (2018). Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center. Nucleic Acids Research, doi:10.1093/nar/gkx1308
  • Korostelev and Noller HF. (2007). The ribosome in focus: new structures bring new insights.
    Trends Biochem. Sci. 32:434-441.
  • Steitz TA. and Moore P. (2003) RNA, the first macromolecular catalyst: the ribosome is a ribozyme.
    Trends Biochem. Sci. 28:411-418.
  • Leung et al. (2011). The mechanism of peptidyl transfer catalysis by the ribosome.
    Annu. Rev. Biochem. 80:527-555.
  • Wilson DN. and Nierhaus KH. (2003).The ribosome through the looking glass.
    Angew. Chem. 42:3464-3486.
  • Simonovic M. and Steitz TA. (2009). A structural view on the mechanism of ribosome-catalyzed peptide bond formation.
    Biochim. Biophys. Acta 1789:612-623.

 

Back to project