- Follow @NCCR_RNADisease
- Stereorandomized Oncocins with Preserved Ribosome...Ribosomal RNA expansion... Evolving precision: rRNA expansion... The human vault RNA enhances tumorigenesis and...rRNA expansion segment 27Lb modulates the factor recruitment ....Loss of the ribosomal RNA methyltransferase NSUN5 ....mRNA-specific translation regulation by a ribosome ....Atomic mutagenesis of stop codon nucleotides ...
- Atomic mutagenesis of the ribosome
- The regulatory non-coding RNA interactome of translating ribosomesThe elusive molecular biology of the vault RNA
Recent Publications
Projects
RNA Gallery
The elusive molecular biology of the vault RNA
Project-relevant publications (own)
- Stefano Gallo, EunBin Kong, Iolanda Ferro and Norbert Polacek (2022). Small but Powerful: The Human Vault RNAs as Multifaceted Modulators of Pro-Survival Characteristics and Tumorigenesis. Cancers 2022, 14, 2787. https://doi.org/10.3390/cancers14112787.
- Ferro I., Gavini J., Gallo S., Bracher L., Landolfo M., Candinas D., Stroka D. M. and Polacek N. (2022). The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma. Autophagy 2022 Jan;18(1):191-203. doi: 10.1080/15548627.2021.1922983.
- Bracher, L.; Ferro, I.; Pulido-Quetglas, C.; Ruepp, M.-D.; Johnson, R. and Polacek, N. (2020). Human vtRNA1-1 Levels Modulate Signaling Pathways and Regulate Apoptosis in Human Cancer Cells. Biomolecules 2020, 10, 614.
- Hüttenhofer, A., Schattner, P. and Polacek, N. (2005). Non-coding RNAs: hope or hype?
Trends in Genet. 21:289-297. - Mrazek, J., Kreutmayer, S. B., Grässer, F. A., Polacek, N., and Hüttenhofer, A.(2007). Subtractive hybridization identifies novel differentially expressed ncRNA species in EBV-infected human B cells.
Nucleic Acids Res. 35: e73. - Nandy, C., Mrazek, J., Stoiber, H., Grässer, F.A., Hüttenhofer, A., and Polacek, N. (2009). Epstein-Barr virus-induced expression of a novel human vault RNA.
J. Mol. Biol. 388:776-784. - Amort M., Nachbauer B., Tuzlak S., Kieser A., Schepers A., Villunger A. and Polacek N. (2015). Expression of the vault RNA protects cells from undergoing apoptosis. Nat Commun. May 8; 6:7030. doi: 10.1038/ncomms8030.