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- Oxidative Damage of RNA: Structure, Function, and... Mammalian In Vitro Translation... The human vault RNA enhances tumorigenesis and...rRNA expansion segment 27Lb modulates the factor recruitment ....Loss of the ribosomal RNA methyltransferase NSUN5 ....mRNA-specific translation regulation by a ribosome ....Atomic mutagenesis of stop codon nucleotides ...
- Atomic mutagenesis of the ribosome
- The regulatory non-coding RNA interactome of translating ribosomesThe elusive molecular biology of the vault RNA
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The regulatory non-coding RNA interactome of translating ribosomes
Project-relevant publications (own)
- Pinel-Marie M.-L., Brielle R., Riffaud C., Germain-Amiot N., Polacek N. and Felden B. (2021). RNA antitoxin SprF1 binds ribosomes to attenuate translation and promote persister cell formation in Staphylococcus aureus. Nat Microbiol 2021 Jan 4. doi: 10.1038/s41564-020-00819-2.
- Gonskikh Y., Gerstl M., Kos M., Borth N., Schosserer M., Grillari J. & Polacek N. (2020). Modulation of mammalian translation by a ribosome-associated tRNA half. RNA Biol., doi.org/10.1080/15476286.2020.1744296
- Fricker R. et al. (2019). A tRNA half modulates translation as stress response in Trypanosoma brucei.
Nat Commun. 10;10(1):118. - Wyss L. et al. (2018). mRNA-specific translation regulation by a ribosome-associated ncRNA in Haloferax volcanii.
Sci Rep. 21;8(1):12502.
- Gebetsberger, J., Wyss, L., Mleczko, A.M., Reuther, J., and Polacek, N. (2016). A tRNA-derived fragment competes with mRNA for ribosome binding and regulates translation during stress. RNA Biol., doi.org/10.1080/15476286.2016.1257470
- Hüttenhofer, A., Schattner, P., and Polacek, N. (2005). Non-coding RNAs: hope or hype?
Trends Genet. 21:289-297. - Zywicki, M., Bakowska-Zywicka, K., and Polacek, N. (2012). Revealing stable processing products from ribosome-associated small RNAs by deep-sequencing data analysis.
Nucleic Acids Res., 40:4013-4024. - Gebetsberger, J., Zywicki, M., Künzi, A. and Polacek N. (2012). tRNA-Derived Fragments Target the Ribosome and Function as Regulatory Non-Coding RNA in Haloferax volcanii. Archea doi:10.1155/2012/260909
- Polacek N., Gebetsberger J. (2013). Slicing tRNAs to boost functional ncRNA diversity.RNA Biol., 10:1798-1806
- Pircher, A., Bakowska-Zywicka, K., Schneider, L., Zywicki, M., and Polacek, N. (2014).
An mRNA-derived noncoding RNA targets and regulates the ribosome. Mol. Cell 54: 147-155.